Endocrine Abstracts

Introduction: Kisspeptins and their cognate receptor GPR-54 (Kiss-1) were found to be regulators of the hypothalamo-pituitary–gonadal axis. It is under debate if the onset of central precocious puberty (CPP) could be triggered by early increase of kisspeptin. We aimed to assess serum kisspeptin levels in girls in order to evaluate its potential as a reliable biochemical marker for differential diagnosis of CPP.Materials and methods: The girls enroll...

Background: The prevalence of precocious puberty (PP) and its relationship to optic pathway tumours in patients suffering from neurofibromatosis type 1 (NF1) is significantly greater than in normal population.Objectives: We present a rare case of precocious puberty in neurofibromatosis type 1 which is not associated with optic pathway tumour but with a tuber cinereum hamartoma.Case report: We present the case of a 5-year and 5-mont...

Insulin resistance is possibly playing an underlying pathogenic role in the polycystic ovary syndrome (PCOS) and although is not a part of its definition, it appears in 50-90% of PCOS women. Polycystic ovary syndrome is also frequently associated with obesity; women suffering of PCOS seem to be at a great risk of developing a metabolic syndrome.Objectives: The aim of our study was to determine the prevalence of the metabolic syndrome in a population of 4...

Introduction: The prevalence of obesity in children and adolescents has dramatically increased over the last 20–30 years.Childhood overweight is associated with higher risk of obesity into adulthood and a higher incidence of metabolic consequences.Objectives: To identify the prevalence of metabolic complications in obese children and adolescents.Methods: One thirty-two obese children and adolescents (age...

Introduction: Tuberculosis is an insidious disease and may be diagnosed after it afected many organs.Case presentation: We present the case of a 56 years old female, who followed antituberculosis treatment in 2003 for pulmonary tuberculosis and during the treatment developed acute renal failure and for this reason the treatment was stopped. During the evaluations a left kidney tumor was detected. Left nephrectomy was performed in 2003 (HP examination &#1...

Introduction: Thyroid cancer in childhood and adolescence represents 1.5–3% of all carcinomas in this group of age. Our purpose is to define clinical and pathological features, therapeutical complications and follow-up characteristics and survival of a group of children and adolescents with thyroid carcinomas.Design: We report a retrospective study of 26 children and adolescents with thyroid carcinoma who were investigated in our institution from Ja...